Penn Neurodegeneration Genomics Center (PNGC) is part of the Department of Pathology and Laboratory Medicine, in the Perelman School of Medicine, at the University of Pennsylvania.

PNGC studies genetics of Alzheimer’s Disease and other related dementia. Our researchers apply high throughput genotyping and sequencing technologies to analyze tens of thousands of genomes and find novel genes. New experimental approaches, algorithms, and databases are developed in order to translate these findings into biological knowledge about the disease and new directions for drug discovery and preventive strategies.

PNGC supports the following scientific and educational activities:

  • Lead large genetics/genomics collaborations
  • Research new experimental and computational approaches
  • Develop computational/experimental resources for nationwide and international projects
  • Provide education and training for next-generation scientists in related area

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