PNGC Blog

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ACAD Recieves $40.5M Grant from NIH

The Asian Cohort for Alzheimer’s Disease (ACAD) has received a $40.5M grant from the National Insitute of Aging (NIA) that will fund the study’s research for the next five years. ACAD recruits Asian Americans and Canadians in nine research sites across North America to study Alzheimer’s genetics. UPenn is one of 16 research centers where […]

Dr. Gerard Schellenberg Honored by Brightfocus

Our very own Dr. Gerard Schellenberg, co-director of PNGC, has been honored by the Brightfocus Foundation for his extensive work in linking genetics and Alzheimer’s research. The honor recognizes exemplary scientists making breakthroughs to cure various diseases. Read more about the award and ceremony here.

PNGC Mourns the Passing of Dr. Christopher (Casey) Brown

PNGC is deeply saddened with the tragic loss of our friend and colleague, Dr. Christopher (Casey) Brown. Casey was a brilliant scientist and made significant contributions in Genetics of Gene Regulation in Alzheimer’s disease. We will miss him dearly and will fondly remember his kindness, charisma, and his dedication to mentoring students and postdoctoral researchers. […]

ADSP Releases Additional 19K Whole Genomes via NIAGADS DSS

On October 6, 2022, the Alzheimer’s Disease Sequencing Project (ADSP) released a new dataset comprised of 19,456 newly sequenced genomes together with joint genotype calls totaling 36,361 genomes with previously released genomes. The data release includes sequencing reads in the CRAM file format, individual sample genotype calls in the genomic Variant Call Format (gVCF), and […]

PNGC Team Advances Methods to Identify Copy Number Variants in Alzheimer’s

By Ulli Hain, Lumina Corps. As a statistical geneticist, Dr. Jung-Ying Tzeng, Professor of Statistics at North Carolina State University and an affiliate faculty member of the Penn Neurodegeneration Genomics Center (PNGC) faculty, enjoys tackling big challenges in omics. “The work is motivated by what’s encountered in real life. You look at the needs from […]

NIA Alzheimer’s Disease Genetics Portfolio, ADSP and Data Sharing

Check out the latest NIA blog post by Marilyn Miller which highlights how to access data generated by the Alzheimer’s Disease Sequencing Project (ADSP) and what new resources are available to researchers. The NIA has also made recent updates to the following pages NIA Alzheimer’s Disease Genetics Portfolio and Alzheimer’s Disease Sequencing Project Consortia. Special […]

Cross-disciplinary Approaches to Alzheimer’s: Training the Next Generation

by Ulli Hain, NOVA Research Company/Lumina Corps “A cross-disciplinary approach to research is essential to understand the complex heterogeneity of Alzheimer’s and other related dementia (ADRD),” said Dr. Corey McMillan, a Penn Neurodegeneration Genomics Center (PNGC) faculty member and associate professor of Neurology. The PNGC uses an interdisciplinary and collaborative approach to studying the genetics […]

NCRAD-ACAD collaboration to study plasma biomarkers for Alzheimer’s disease diagnosis in Asian populations

The Asian Cohort for Alzheimer’s Disease (ACAD) is pleased to announce a partnership with National Centralized Repository for Alzheimer’s Disease and Related Dementias (NCRAD) to analyze biosamples collected through ACAD sites. In the next few months, we will begin analyzing over 100 plasma samples collected through ACAD, and an additional 300+ plasma samples from co-enrolled […]

Penn Launches New Training Program in Translational Neuroimaging for Alzheimer’s and Related Dementias

By Ulli Hain, NOVA Research Company/Lumina Corps PNGC is thrilled to announce a new predoctoral and postdoctoral training program on Translational Neuroimaging in Alzheimer’s Disease and Related Dementias (ADRD). The program is directed by Dr. Corey McMillan, Associate Professor of Neurology and a PNGC faculty member, and has several PNGC faculty trainers including Drs. Li-San […]

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