Penn Neurodegeneration
Genomics Center

Penn Neurodegeneration Genomics Center (PNGC) is offering a Pilot AI Learning Series this semester.  Now underway, it brings together opportunities for discussion and practical training for researchers, trainees, and staff interested in applying AI tools to biomedical research and administrative workflows.  All sessions are held in person, with required registration and limited space. Dates, session […]

Genome sequencing results can be used to train PRS models but suffer from computation and privacy limitations. A new web portal from Drs. Jin Jin and Bingxin Zhao uses GWAS summary statistics and novel pseudo-training methods to make the latest generation of PRS models more accessible. 

ur first batch of genetic data is available, and the quality is outstanding, indicating the sample collection protocol is robust. Since most ACAD participants are immigrants, immigration experience (languages, education, occupation transitions) could be a unique feature in disease development. Analyzing lifestyle data highlights the importance of the environment in AD risks and how genetics may interact with major life transitions.

The Alzheimer’s Genomics Database is a user-friendly AD-centric interactive knowledgebase and genome browser, which provides unrestricted access to GWAS summary statistics from the NIAGADS repository, as well as to annotated variants called from ongoing the Alzheimer’s Disease Sequencing Project’s (ADSP) joint-genotype calling efforts.  We sat down with Dr. Emily Greenfest-Allen, the architect of the Alzheimer’s Genomics Database, […]

Sixth year PHD Student, Kaylyn Clark discusses how she found herself in genetics and where she sees her future.

Visualization of hipFG