NIAGADS is the NIA Genetics of Alzheimer’s Disease Data Storage Site. NIAGADS is a genetics data repository set up by the National Institute of Aging (NIA) to facilitate access by qualified investigators to genotypic data for Alzheimer’s disease (AD). We propose to expand NIAGADS into a one-stop shopping data warehouse and portal for AD genetics that reflects the latest advances in genetics research and high-throughput genotyping and next-generation sequencing technologies. The completed repository will include a genomics database for AD genetics; enhancement for next-generation sequencing data, secondary data, and analysis results; and accessible workflows and secondary data from various AD genetics projects.