NIAGADS Receives $23.9 Million Five-Year Renewal

PNGC is excited to announce that The National Institute on Aging Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS) has received a 5-year grant renewal totaling up to $23.9 million to continue their work. NIAGADS is a genetics data repository set up by the National Institute of Aging (NIA) to facilitate access by qualified investigators to genotypic data for Alzheimer’s disease (AD). NIAGADS is led by Li-San Wang, PhD, Co-Director of PNGC and a Professor of Pathology and Laboratory Medicine at the Perelman School of Medicine.

Dr. Wang and his team will continue the mission of NIAGADS as the national repository for AD genetics and genomics. The site currently houses 84 data sets from Genome-Wide Association Studies (GWAS), whole-genome and whole-exome sequencing, and other genomic data types made up of more than 113,000 samples. The site is also the data coordinating center for Alzheimer’s Disease Sequencing Project (ADSP), a key initiative to meet goals of the National Plan to Address Alzheimer’s Disease (NAPA). ADSP plans to sequence and analyze 80,000 genomes from multi-ethnic populations by 2023 in order to find novel genetic variants modulating AD risk. During the next five-year funding period, NIAGADS will establish ADSP as a rich, lasting AD genetics and genomics resource and facilitate use of this resource by researchers to a deeper understanding of AD and discovery of new approaches for treatment and prevention.

NIAGADS is supported by additional leadership from Co-PI Gerard Schellenberg, along with Co-Investigators Adam Naj, Yuk Yee Leung, Wan-Ping Lee, David Wolk, and Jacob Gardner at the University of Pennsylvania, Jung-Ying Tzeng at North Carolina State University, and Shin-Yi Chou at Lehigh University.

This research is supported by the National Institute on Aging of the National Institutes of Health grant number 2U24AG041689-11.

To learn more about NIAGADS or to apply for data, visit www.niagads.org

Leave a Reply

Your email address will not be published.

Sign up to receive journal club/seminar announcements