ur first batch of genetic data is available, and the quality is outstanding, indicating the sample collection protocol is robust. Since most ACAD participants are immigrants, immigration experience (languages, education, occupation transitions) could be a unique feature in disease development. Analyzing lifestyle data highlights the importance of the environment in AD risks and how genetics may interact with major life transitions.
The Alzheimer’s Genomics Database is a user-friendly AD-centric interactive knowledgebase and genome browser, which provides unrestricted access to GWAS summary statistics from the NIAGADS repository, as well as to annotated variants called from ongoing the Alzheimer’s Disease Sequencing Project’s (ADSP) joint-genotype calling efforts. We sat down with Dr. Emily Greenfest-Allen, the architect of the Alzheimer’s Genomics Database, […]
Sixth year PHD Student, Kaylyn Clark discusses how she found herself in genetics and where she sees her future.
Visualization of hipFG
Last month, PNGC had the pleasure of hosting Dr. Towfique Raj, PhD in partnership with the Perelman School of Medicine for the Biomedical Data Science Seminar Series. Dr. Raj is an Associate Professor of Neuroscience at the Icahn School of Medicine at Mount Sinai. His seminar addressed the post-GWAS challenges of variant and gene prioritization. […]
Dr. Barbara Spencer is a Postdoctoral Fellow working with Corey McMillan in the Penn FTD Center. She joined Penn in 2020 after receiving a PhD in Neurosciences from UC San Diego. Her research looks into disentangling heterogeneity in the FTD-ALS spectrum using genotype and transcriptomic approaches. We talked with Dr. Spencer about her journey in neurodegenerative […]
PNGC co-director, Dr. Li-San Wang, presented at the Illuminating Alzheimer’s Disease Genetic Architecture via Diversity webinar. The program explored the lack of genome research for Black, Latino, and Asian populations and highlighted the organizations fighting for more. Dr. Wang discussed the need for more research infrastructure to study AD in Asian Americans and Pacific Islanders […]
Tiffany Chow is a new professor of Pathology and Laboratory Medicine at Penn working at PNGC and ACAD
The Asian Cohort for Alzheimer’s Disease (ACAD) has received a $40.5M grant from the National Insitute of Aging (NIA) that will fund the study’s research for the next five years. ACAD recruits Asian Americans and Canadians in nine research sites across North America to study Alzheimer’s genetics. UPenn is one of 16 research centers where […]
NIAGADS is featured on the Amazon Web Services (AWS) blog for its work on Alzheimer’s Disease genetics data sharing. NIAGADS uses the AWS platform extensively to host and share large amounts of genome sequence data with the entire research community. Follow the link to read the blog post.
Our very own Dr. Gerard Schellenberg, co-director of PNGC, has been honored by the Brightfocus Foundation for his extensive work in linking genetics and Alzheimer’s research. The honor recognizes exemplary scientists making breakthroughs to cure various diseases. Read more about the award and ceremony here.
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