A recent preprint by Dr. Anil Wadhwani and Dr. David Goldberg presents machine learning models capturing brain p-tau in different pathological contexts. Alzheimer’s disease is marked by buildups of proteins within and around brain cells that can impede function and eventually lead to cell death. Two proteins, Amyloid-beta (AB) and Tau, can each form aggregates […]
Penn Neurodegeneration Genomics Center (PNGC) is offering a Pilot AI Learning Series this semester. Now underway, it brings together opportunities for discussion and practical training for researchers, trainees, and staff interested in applying AI tools to biomedical research and administrative workflows. All sessions are held in person, with required registration and limited space. Dates, session […]
Genome sequencing results can be used to train PRS models but suffer from computation and privacy limitations. A new web portal from Drs. Jin Jin and Bingxin Zhao uses GWAS summary statistics and novel pseudo-training methods to make the latest generation of PRS models more accessible.
Sixth year PHD Student, Kaylyn Clark discusses how she found herself in genetics and where she sees her future.
PNGC co-director, Dr. Li-San Wang, presented at the Illuminating Alzheimer’s Disease Genetic Architecture via Diversity webinar. The program explored the lack of genome research for Black, Latino, and Asian populations and highlighted the organizations fighting for more. Dr. Wang discussed the need for more research infrastructure to study AD in Asian Americans and Pacific Islanders […]
Tiffany Chow is a new professor of Pathology and Laboratory Medicine at Penn working at PNGC and ACAD
NIAGADS is featured on the Amazon Web Services (AWS) blog for its work on Alzheimer’s Disease genetics data sharing. NIAGADS uses the AWS platform extensively to host and share large amounts of genome sequence data with the entire research community. Follow the link to read the blog post.
Our very own Dr. Gerard Schellenberg, co-director of PNGC, has been honored by the Brightfocus Foundation for his extensive work in linking genetics and Alzheimer’s research. The honor recognizes exemplary scientists making breakthroughs to cure various diseases. Read more about the award and ceremony here.
For our first Graduate Student Profile, we sat down with Beth Burton to discuss how she found a passion for genomics and her future in the field
On October 27-30, ASHG members and leading scientists worldwide presented their research findings to the American Society of Human Genetics (ASHG) 2020 Virtual Meeting. Among them were several Penn Neurodegeneration Genomics Center (PNGC) members who had the opportunity to learn from and share their latest updates with the genetics and genomics research community. Pavel Kuksa, […]
A team of researchers led by Li-San Wang, PhD, Professor of Pathology and Laboratory Medicine in the Perelman School of Medicine at the University of Pennsylvania, has been awarded a two-year pilot grant expected to total $4.8 million from the National Institute on Aging (NIA) to study the genetics of Alzheimer’s disease in people of […]
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