PNGC Congratulates Dr. Leung on BAND3 Award

PNGC is pleased to announce that Dr. Fanny Leung, Research Assistant Professor at the University of Pennsylvania and PNGC faculty member, recently had an application funded under the 2019 Biomarkers Across Neurodegenerative Diseases (BAND 3) Program. This award is sponsored by The Alzheimer’s Association, Alzheimer’s Research UK (ARUK), The Michael J. Fox Foundation for Parkinson’s Research (MJFF), and the Weston Brain […]

DASHR 2.0 Released: Integrated database of human small non-coding RNA genes and mature products

PNGC is pleased to announce the release of the DASHR v2.0 database of human small non-coding RNAs (sncRNAs). DASHR v2.0 is freely available at https://lisanwanglab.org/DASHRv2. This is an extremely useful resource and reference for the community studying non-coding RNAs and their diverse roles in often tissue-specific cellular processes related to human diseases. DASHR (Database of […]

Penn Medicine Press Release Highlights New Data Sharing Service

Recently, Penn Medicine News wrote a press release describing the new NIAGADS Data Sharing Service (DSS), which will distribute genomic data to qualified investigators.  Initially, whole-genome sequence data will be available for 5,000 subjects, with more data to be released within a year. “Genetic findings for Alzheimer’s disease are critical for identifying targets for therapeutic […]

SPAR: Small RNA-seq Portal for analysis of sequencing expeRiments

PNGC is pleased to announce the release of the SPAR web server for small RNA-seq data analysis. Small non-coding RNAs (<200 nts, sncRNAs) play important regulatory roles by binding to mRNA and associating with transcription factor complexes in most eukaryotes, but only a fraction of sncRNAs, which include many different classes, have been identified and […]

PNGC Releases INFERNO

PNGC is pleased to announce the release of the INFERNO (INFERing the molecular mechanisms of NOncoding genetic variants) method (http://inferno.lisanwanglab.org). Since the majority of variants that genome-wide association studies (GWAS) identify are outside of protein-coding genes and may be proxies of truly causal variants that are inherited together in linkage disequilibrium (LD), there is a […]

Li-San Wang Quoted in CBS Article

“Can the machine invasion help save your brain?” CBS explores this question in an October 27 article about the development of technology as it relates to advances in Alzheimer’s disease. While the amount of genetic data available has increased in recent years, the speed at which it gets sifted through also needs to increase in […]

Sign up to receive journal club/seminar announcements