Penn Neurodegeneration Genomics Center (PNGC) is offering a Pilot AI Learning Series this semester. Now underway, it brings together opportunities for discussion and practical training for researchers, trainees, and staff interested in applying AI tools to biomedical research and administrative workflows. All sessions are held in person, with required registration and limited space. Dates, session […]
PNGC is excited to launch a new AI Learning Series featuring an ethics-focused journal club and practical seminars. AI Ethics Journal ClubThese discussions will cover key issues in AI ethics, including bias and fairness in biomedical models, data governance, and responsible use of generative AI. Participants will receive a short reading list before each session. Our […]
Genome sequencing results can be used to train PRS models but suffer from computation and privacy limitations. A new web portal from Drs. Jin Jin and Bingxin Zhao uses GWAS summary statistics and novel pseudo-training methods to make the latest generation of PRS models more accessible.
ur first batch of genetic data is available, and the quality is outstanding, indicating the sample collection protocol is robust. Since most ACAD participants are immigrants, immigration experience (languages, education, occupation transitions) could be a unique feature in disease development. Analyzing lifestyle data highlights the importance of the environment in AD risks and how genetics may interact with major life transitions.
The Alzheimer’s Genomics Database is a user-friendly AD-centric interactive knowledgebase and genome browser, which provides unrestricted access to GWAS summary statistics from the NIAGADS repository, as well as to annotated variants called from ongoing the Alzheimer’s Disease Sequencing Project’s (ADSP) joint-genotype calling efforts. We sat down with Dr. Emily Greenfest-Allen, the architect of the Alzheimer’s Genomics Database, […]
Sixth year PHD Student, Kaylyn Clark discusses how she found herself in genetics and where she sees her future.
Visualization of hipFG
Last month, PNGC had the pleasure of hosting Dr. Towfique Raj, PhD in partnership with the Perelman School of Medicine for the Biomedical Data Science Seminar Series. Dr. Raj is an Associate Professor of Neuroscience at the Icahn School of Medicine at Mount Sinai. His seminar addressed the post-GWAS challenges of variant and gene prioritization. […]
Dr. Barbara Spencer is a Postdoctoral Fellow working with Corey McMillan in the Penn FTD Center. She joined Penn in 2020 after receiving a PhD in Neurosciences from UC San Diego. Her research looks into disentangling heterogeneity in the FTD-ALS spectrum using genotype and transcriptomic approaches. We talked with Dr. Spencer about her journey in neurodegenerative […]
PNGC co-director, Dr. Li-San Wang, presented at the Illuminating Alzheimer’s Disease Genetic Architecture via Diversity webinar. The program explored the lack of genome research for Black, Latino, and Asian populations and highlighted the organizations fighting for more. Dr. Wang discussed the need for more research infrastructure to study AD in Asian Americans and Pacific Islanders […]
Tiffany Chow is a new professor of Pathology and Laboratory Medicine at Penn working at PNGC and ACAD
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