PNGC Blog

Our random and intentional thoughts

Genome Center for Alzheimer’s Disease Receives $20 Million Five-Year Renewal

PNGC is excited to announce that the Genome Center for Alzheimer’s Disease (GCAD) has received a 5-year grant renewal totaling $20 million to continue their work. GCAD, a collaborative research center between Penn, Boston University, Case Western Reserve University, Columbia University, the University of Miami, and the University of Indiana, aims to identify AD-related genes […]

CADRE/ADGC Announce Trans-Institutional Seminar Series

The Collaborative for Alzheimer’s Disease Research (CADRE) and the Alzheimer’s Disease Genetics Consortium (ADGC) are creating a new multi-institutional seminar series to support next generation researchers in Alzheimer’s disease process, diagnosis and care by encouraging collaboration within the AD research community. The new Trans-Institutional Seminar Series will highlight up-and-coming junior investigators to help strengthen their […]

Alessandra Chesi, PhD: Advancing Toward Druggable Targets

By Kathy Sedgwick, NOVA Research Company Dr. Alessandra Chesi joined the University of Pennsylvania faculty as an Assistant Professor of Pathology and Laboratory Medicine in July 2020. Her work at Penn focuses on the application of transformative technologies as well as functional genomics and systems biology approaches toward gaining insight into the regulation and identity […]

PNGC Co-Director Li-San Wang to Present at the 2021 NIH Alzheimer’s Research Summit

The NIH will host their 2021 Alzheimer’s Research Summit April 19-22. This virtual summit will convene leading AD scientists, innovators, and public health advocates to showcase progress in Alzheimer’s disease research and ideas for supporting the goal of precision medicine for Alzheimer’s treatment and prevention. On Tuesday, April 20, Drs Li-San Wang (Penn) and Timothy […]

The NIA Announces New Website

The National Institute on Aging (NIA) recently announced a new resource that will help teach and assist those whose lives are affected by Alzheimer’s disease and related dementias. Alzheimers.gov is a website that serves as the federal government portal for dementia information and resources. To create Alzheimers.gov, the NIA worked with individuals living with dementia, […]

Lauren Kleidermacher Receives Thouron Award

University of Pennsylvania senior and PNGC undergraduate researcher Lauren Kleidermacher was awarded the Thouron Award to pursue her graduate studies in the United Kingdom. The award was established in 1960 by John Thouron and his wife, Esther du Pont Thouron, to promote closer ties between the U.K. and the United States. The award covers full […]

NIAGADS DSS Releases Additional 17K Whole Genomes

NIAGADS is pleased to announce the release of whole genome sequencing (WGS) data from 16,906 samples through the Data Sharing Service (DSS). The data release includes CRAMs, gVCFs, and project-level VCFs across all samples. The pVCF released here is provided as a preview to the formal ADSP quality control that will be released in a few months.

The American Society of Human Genetics (ASHG) 2020 Virtual Meeting

On October 27-30, ASHG members and leading scientists worldwide presented their research findings to the American Society of Human Genetics (ASHG) 2020 Virtual Meeting. Among them were several Penn Neurodegeneration Genomics Center (PNGC) members who had the opportunity to learn from and share their latest updates with the genetics and genomics research community. Pavel Kuksa, […]

NIA Funds Two-Year Pilot Grant to Study Genetics of Alzheimer’s Disease in People of Asian Heritage

A team of researchers led by Li-San Wang, PhD, Professor of Pathology and Laboratory Medicine in the Perelman School of Medicine at the University of Pennsylvania, has been awarded a two-year pilot grant expected to total $4.8 million from the National Institute on Aging (NIA) to study the genetics of Alzheimer’s disease in people of […]

Alzheimer’s Disease Variant Portal

Alzheimer’s disease (AD) is one of the most serious public health challenges that affect the nation. Both the direct and indirect costs of AD have been stressing the healthcare system. The cause of AD, however, is still unknown. The recent development of genome-wide association studies (GWASs) has been a powerful tool for discovering thousands of […]

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