A Researcher, Musician, and Philly Sports Fan: Beth Burton
For our first Graduate Student Profile, we sat down with Beth Burton to discuss how she found a passion for genomics and her future in the field
PNGC Mourns the Passing of Dr. Christopher (Casey) Brown
PNGC is deeply saddened with the tragic loss of our friend and colleague, Dr. Christopher (Casey) Brown. Casey was a brilliant scientist and made significant contributions in Genetics of Gene Regulation in Alzheimer’s disease. We will miss him dearly and will fondly remember his kindness, charisma, and his dedication to mentoring students and postdoctoral researchers. […]
ADSP Releases Additional 19K Whole Genomes via NIAGADS DSS
On October 6, 2022, the Alzheimer’s Disease Sequencing Project (ADSP) released a new dataset comprised of 19,456 newly sequenced genomes together with joint genotype calls totaling 36,361 genomes with previously released genomes. The data release includes sequencing reads in the CRAM file format, individual sample genotype calls in the genomic Variant Call Format (gVCF), and […]
PNGC Team Advances Methods to Identify Copy Number Variants in Alzheimer’s
By Ulli Hain, Lumina Corps. As a statistical geneticist, Dr. Jung-Ying Tzeng, Professor of Statistics at North Carolina State University and an affiliate faculty member of the Penn Neurodegeneration Genomics Center (PNGC) faculty, enjoys tackling big challenges in omics. “The work is motivated by what’s encountered in real life. You look at the needs from […]
NIA Alzheimer’s Disease Genetics Portfolio, ADSP and Data Sharing
Check out the latest NIA blog post by Marilyn Miller which highlights how to access data generated by the Alzheimer’s Disease Sequencing Project (ADSP) and what new resources are available to researchers. The NIA has also made recent updates to the following pages NIA Alzheimer’s Disease Genetics Portfolio and Alzheimer’s Disease Sequencing Project Consortia. Special […]
Cross-disciplinary Approaches to Alzheimer’s: Training the Next Generation
by Ulli Hain, NOVA Research Company/Lumina Corps “A cross-disciplinary approach to research is essential to understand the complex heterogeneity of Alzheimer’s and other related dementia (ADRD),” said Dr. Corey McMillan, a Penn Neurodegeneration Genomics Center (PNGC) faculty member and associate professor of Neurology. The PNGC uses an interdisciplinary and collaborative approach to studying the genetics […]
NCRAD-ACAD collaboration to study plasma biomarkers for Alzheimer’s disease diagnosis in Asian populations
The Asian Cohort for Alzheimer’s Disease (ACAD) is pleased to announce a partnership with National Centralized Repository for Alzheimer’s Disease and Related Dementias (NCRAD) to analyze biosamples collected through ACAD sites. In the next few months, we will begin analyzing over 100 plasma samples collected through ACAD, and an additional 300+ plasma samples from co-enrolled […]
Penn Launches New Training Program in Translational Neuroimaging for Alzheimer’s and Related Dementias
By Ulli Hain, NOVA Research Company/Lumina Corps PNGC is thrilled to announce a new predoctoral and postdoctoral training program on Translational Neuroimaging in Alzheimer’s Disease and Related Dementias (ADRD). The program is directed by Dr. Corey McMillan, Associate Professor of Neurology and a PNGC faculty member, and has several PNGC faculty trainers including Drs. Li-San […]
NIAGADS Receives $23.9 Million Five-Year Renewal
PNGC is excited to announce that The National Institute on Aging Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS) has received a 5-year grant renewal totaling up to $23.9 million to continue their work. NIAGADS is a genetics data repository set up by the National Institute of Aging (NIA) to facilitate access by qualified investigators […]
PNGC Mourns the Passing of Dr. John Q. Trojanowski
PNGC is saddened with the news of the passing of Professor John Q. Trojanowski. The scientific community lost a visionary leader, and we at PNGC all mourn the loss of a dear friend, a generous colleague, and a caring mentor. PNGC is part of the enormous legacy that Dr. Trojanowski had left to Penn, as […]
FILER: a framework for harmonizing and querying large-scale functional genomics knowledge
PNGC is pleased to announce the release of the FILER, a functional genomics repository developed by NIAGADS, now published in NAR Genomics and Bioinformatics. Functional genomic and annotation data such as tissue-specific regulatory/enhancer elements, transcription factor binding, chromatin states, and interactions are widely used in systems biology, genetic and genomic studies, e.g., to interpret non-coding […]