PNGC Team Advances Methods to Identify Copy Number Variants in Alzheimer’s

By Ulli Hain, Lumina Corps. As a statistical geneticist, Dr. Jung-Ying Tzeng, Professor of Statistics at North Carolina State University and an affiliate faculty member of the Penn Neurodegeneration Genomics Center (PNGC) faculty, enjoys tackling big challenges in omics. “The work is motivated by what’s encountered in real life. You look at the needs from […]

NIA Alzheimer’s Disease Genetics Portfolio, ADSP and Data Sharing

Check out the latest NIA blog post by Marilyn Miller which highlights how to access data generated by the Alzheimer’s Disease Sequencing Project (ADSP) and what new resources are available to researchers. The NIA has also made recent updates to the following pages NIA Alzheimer’s Disease Genetics Portfolio and Alzheimer’s Disease Sequencing Project Consortia. Special […]

Cross-disciplinary Approaches to Alzheimer’s: Training the Next Generation

by Ulli Hain, NOVA Research Company/Lumina Corps “A cross-disciplinary approach to research is essential to understand the complex heterogeneity of Alzheimer’s and other related dementia (ADRD),” said Dr. Corey McMillan, a Penn Neurodegeneration Genomics Center (PNGC) faculty member and associate professor of Neurology. The PNGC uses an interdisciplinary and collaborative approach to studying the genetics […]

NCRAD-ACAD collaboration to study plasma biomarkers for Alzheimer’s disease diagnosis in Asian populations

The Asian Cohort for Alzheimer’s Disease (ACAD) is pleased to announce a partnership with National Centralized Repository for Alzheimer’s Disease and Related Dementias (NCRAD) to analyze biosamples collected through ACAD sites. In the next few months, we will begin analyzing over 100 plasma samples collected through ACAD, and an additional 300+ plasma samples from co-enrolled […]

Penn Launches New Training Program in Translational Neuroimaging for Alzheimer’s and Related Dementias

By Ulli Hain, NOVA Research Company/Lumina Corps PNGC is thrilled to announce a new predoctoral and postdoctoral training program on Translational Neuroimaging in Alzheimer’s Disease and Related Dementias (ADRD). The program is directed by Dr. Corey McMillan, Associate Professor of Neurology and a PNGC faculty member, and has several PNGC faculty trainers including Drs. Li-San […]

NIAGADS Receives $23.9 Million Five-Year Renewal

PNGC is excited to announce that The National Institute on Aging Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS) has received a 5-year grant renewal totaling up to $23.9 million to continue their work. NIAGADS is a genetics data repository set up by the National Institute of Aging (NIA) to facilitate access by qualified investigators […]

Alzheimer’s Disease Variant Portal (ADVP): The Newest Curated Population-specific Alzheimer’s Disease Genetics Resource

By Fernanda Ruiz, NOVA Research Company Alzheimer’s Disease (AD) is a devastating disease that affects more than 6 million Americans, a number that is projected to increase considerably in the near future. Scientists looking for the causes of AD use different approaches, including genomic studies like genome-wide association studies (GWAS), that detect associations between genetic […]

Structural Variant Toolbox: Discovering, Genotyping, and Merging SVs in Alzheimer’s Disease Research

By Fernanda Ruiz, NOVA Research Company Alzheimer’s disease (AD) is a degenerative disease that likely is caused by a combination of environmental, lifestyle, and genetic factors, and increasing age. Alzheimer’s Disease Sequencing  Project (ADSP) researchers are focused on gaining further insights into the genetic component of this disease, including the role of structural variants (SVs), […]

CADRE/ADGC Announce Trans-Institutional Seminar Series

The Collaborative for Alzheimer’s Disease Research (CADRE) and the Alzheimer’s Disease Genetics Consortium (ADGC) are creating a new multi-institutional seminar series to support next generation researchers in Alzheimer’s disease process, diagnosis and care by encouraging collaboration within the AD research community. The new Trans-Institutional Seminar Series will highlight up-and-coming junior investigators to help strengthen their […]

Alessandra Chesi, PhD: Advancing Toward Druggable Targets

By Kathy Sedgwick, NOVA Research Company Dr. Alessandra Chesi joined the University of Pennsylvania faculty as an Assistant Professor of Pathology and Laboratory Medicine in July 2020. Her work at Penn focuses on the application of transformative technologies as well as functional genomics and systems biology approaches toward gaining insight into the regulation and identity […]

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